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Microencapsulation of tissues and cells for treatment of hormone-related diseases

Project Overview

To design polyethylene glycol diacrylate (PEGdA) hydrogels for the encapsulation of Murine Leydig Tumor Cells (MLTC-1) in an effort to increase cell viability and testosterone secretion. The PEG-dA hydrogels must provide immunoprotection and allow for the effective diffusion of oxygen, nutrients, hormones, and metabolic wastes. The overall goal is to restore the testosterone level of castrated mice via injection or implantation of the PEG-dA encapsulated cells.

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Contact Information

Team Members

  • Albert Kwansa - Team Leader
  • John Harrison - Communicator
  • Jacqueline Wong - BSAC
  • Eric Lee - BWIG

Advisor and Client

  • Prof. William Murphy - Advisor
  • Dr. Craig Atwood - Client

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