Project Overview

Direct measurements of neurochemical substances in the brain from free moving non-human primates is significantly important for understanding complex brain function and developing treatment strategies for brain disorders in humans. Accordingly, our client has modified an existing microdialysis method for application to rhesus monkeys (Frost et al., in press). However, this method requires restraining monkeys in chairs for up to 12 hours while our client collect samples. Thus, the purpose of this project is to develop a device allowing monkeys to be free from chairing while experiments are conducted. Although a similar device is available for other studies involved in blood sampling in non-human primates, the development of the device for microdialysis experiments may require creativity and intellectual exercise.

Files

• Midsemester Presentation (March 7, 2008)
• Midsemester Report (March 11, 2008)
• Final Poster (May 1, 2008)
• Final Report (May 8, 2008)

Contact Information

Team Members

• Kara Barnhart - Team Leader
• Grant Smith - Communicator
• Angwei Law - BSAC
• Paul Schildgen - BWIG

Advisor and Client

• Prof. William Murphy - Advisor
• Dr. Ei Terasawa - Client

Related Projects

• Fall 2009: Device for Shielding a Neurochemical Sampling Apparatus in Non-Human Primate Research
• Spring 2009: Development of a device for neurochemical sample collection from freely moving monkeys
• Fall 2008: Development of a device for neurochemical sample collection from freely moving monkeys
• Spring 2008: Neurochemical Sampling