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Optical measurement of animal tumor volume for cancer research studies

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Project Overview

Cancer researchers often study the effects of various treatments on tumors growing in animals (typically mice). investigators measure tumor growth several times per week and use an estimate of tumor volume calculated based on measurements of "length" and "width". There can be significant day to day and user to user variability leading to a not insignificant amount of uncertainty. This project seeks to develop a quick, reproducible and user-independent method of measuring tumor volume.
Possibilities include using an ipod touch and developing software. may be couple with a light grid projected onto the tumor to aid in contour delineation and size estimates.
For the research project i would envision first measuring the amount of error both within users and between users and using this as a benchmark to improve upon. Could use a 3D printed mouse with a tumor for development purposes.

Depending on the approach there may be IP considerations.

Team Picture

Team members from left to right: Robert Weishar, Junzhou Chen, Frank Seipel, Callie Mataczynski
Team members from left to right: Robert Weishar, Junzhou Chen, Frank Seipel, Callie Mataczynski

Contact Information

Team Members

  • Robert Weishar - Team Leader & Communicator
  • Callie Mataczynski - BSAC
  • Junzhou Chen - BWIG
  • Frank Seipel - BPAG

Advisor and Client

  • Prof. Melissa Skala - Advisor
  • Dr. Randy Kimple - Client

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