Project Overview

2-photon microscopy is a highly useful tool for examining a variety of characteristics. In neuroscience, it has become particularly useful for imaging of synapses in the brain to determine brain function. Other groups have successfully used a cranial window in mice to perform synapse imaging by holding the mouse’s skull rigidly to the stage of the microscope while leaving the body free to move. It is the goal of this project to create a similar device that will allow a mouse’s head to be held in a fixed stereotaxic frame to be used for examination of synapses during sleep and waking periods.

Files

• Mid-Semester Presentation (October 17, 2008)
• Product Design Specifications (Sept 2008) (October 21, 2008)
• Mid-Semester Report (October 22, 2008)
• End of Semester Poster (December 10, 2008)
• Final Report (December 12, 2008)

Contact Information

Team Members

• David Leinweber - Team Leader
• Jonathon Seaton - Communicator
• Mark Reagan - BSAC
• Jay Sekhon - BWIG

Advisor and Client

• Mitchell Tyler - Advisor
• Dr. Ugo Faraguna - Client
• Dr. Giulio Tononi - Alternate Contact