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Noninvasive device monitoring of sarcopenia

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A device that is capable of monitoring and tracking of muscle characteristics, including mass, muscle to fat ratio, and quality of the muscle.

Project Overview

Sarcopenia is a condition that impacts 5-13% of individuals over the age of 60-70, and 11-50% of individuals over the age of 80 [1]. It is defined as a skeletal muscle disorder that accelerates the loss of muscle mass and function, and can lead to increased fall risk, frailty, and overall morbidity [2]. Current methods of measuring muscle mass for diagnosis of the condition include Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and dual energy X-ray absorptiometry (DXA) [2]. Oftentimes these measurements are performed in conjunction with a questionnaire, SARC-F, that evaluates a patient’s subjective perception of their overall strength and mobility [2]. However, these approaches are not widely recognized by physicians, and are typically time-consuming, expensive, and inaccessible to many patients [3]. There is therefore a need for a novel diagnostic device that enables fast, affordable, and accessible measurement and tracking of muscle mass changes over time to support early detection and ongoing monitoring of sarcopenia.

[1] S. von Haehling, J. E. Morley, and S. D. Anker, “An overview of sarcopenia: facts and numbers on prevalence and clinical impact,” J. Cachexia Sarcopenia Muscle, vol. 1, no. 2, pp. 129–133, Dec. 2010, doi: 10.1007/s13539-010-0014-2.
[2]A. J. Cruz-Jentoft and A. A. Sayer, “Sarcopenia,” The Lancet, vol. 393, no. 10191, pp. 2636–2646, Jun. 2019, doi: https://doi.org/10.1016/s0140-6736(19)31138-9.
[3]A. A. Sayer and A. Cruz-Jentoft, “Sarcopenia definition, diagnosis and treatment: consensus is growing,” Age and Ageing, vol. 51, no. 10, Oct. 2022, doi: https://doi.org/10.1093/ageing/afac220.

Team Picture

Liv Baumann, Lia Lejonvarn, Lucia Frieling, Elaina Rizzo, Amanda Kothe
Liv Baumann, Lia Lejonvarn, Lucia Frieling, Elaina Rizzo, Amanda Kothe

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Team Members

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