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Microfluidic chip to isolate midbody remnants or large extracellular vesicles using a magnetic field

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Creating a microfluidic chip that enables accurate and efficient separation, thus facilitating in-depth exploration of the potential roles of the midbody remnants.

Project Overview

The process of mitosis culminates in the formation of three distinct membrane-bound entities. Among these, two are commonly recognized as daughter cells, while the third, less understood component, is the midbody remnant. Historically, the midbody remnant was considered a cellular waste bin, but recent discoveries from the Skop lab propose a more significant role for this structure. To advance our understanding of the midbody remnant's function, the Skop lab seeks a specialized technique for isolating midbody remnants from cell culture media. This method will be implemented through a microfluidic chip, allowing for precise and efficient separation, and enabling further investigation into the potential functions of these intriguing cellular components. Our team will be working on developing the microfluidic chip along with the Skop lab.

Team Picture

Team Picture: Front (left to right): Meghan Detra, Cora Williams, Anna Mercord. Back (left to right): Joel Nitz, Mustafa Al-Sakhbouri
Team Picture: Front (left to right): Meghan Detra, Cora Williams, Anna Mercord. Back (left to right): Joel Nitz, Mustafa Al-Sakhbouri

Contact Information

Team Members

  • Joel Nitz - Team Leader
  • Meghan Detra - Communicator
  • Anna Mercord - BSAC
  • Mustafa Al Sakhbouri - BWIG
  • Cora Williams - BPAG

Advisor and Client

  • Prof. Paul Campagnola - Advisor
  • Dr. Ahna Skop - Client
  • Dr. Sungjin Park - Alternate Contact

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