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Philips: Tissue sensing to guide delivery of endovascular therapy

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Design an impedance sensing drug delivery needle device that can map intravascular artery walls.

Project Overview

Atherectomy is a procedure completed by physicians via minimally invasive techniques to remove atherosclerosis from the vessel. Atherosclerosis is a plaque build-up in the arteries which prevent vital oxygen rich blood from traveling to organs and tissues, causing cell death. There are many methods to remove the plaque like laser ablation or mechanical removal but the likelihood of restenosis is high without further treatment. However, when atherectomy procedures are followed by treatment of Paclitaxel, restenosis is less likely to occur. Paclitaxel maintains patient blood flow after operations and decreases the need for additional procedures. By reducing additional procedures, the risk of injury and death are progressively decreased. The Impedance Sensing Drug Delivery Device is intended to be a Paclitaxel drug delivery system that will administer the drug into the vessel wall via an array of needles guided by impedance sensing. The administration of the drug in the vessel wall aims to decrease wash, ensuring long lasting treatments. The long lasting Paclitaxel treatment allows for fewer future operations while maintaining vessel patency and patent blood flow throughout the vessel system.

Team Picture

From Left to Right: Lakshay Bhandari, Maxwell Milaitis, Zaid Aman, Jessica Hiya
From Left to Right: Lakshay Bhandari, Maxwell Milaitis, Zaid Aman, Jessica Hiya

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Team Members

Advisor and Client

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