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Biogel release to the ocular surface of epithelial growth factors

Design Award

  • Tong Biomedical Design Award Winner

Project Overview

Significant dry eye is an affliction that affects up to ten million people in the United States. There are currently options available to treat the symptoms of dry eye, but a way to treat the causes and repair the damage has yet to be found. We aspire to design and fabricate a dissolving biogel that is capable of sustained release of epidermal growth factors that will work to maintain healthy epithelium and restore damaged tissue on the ocular surface.

Team Picture

From left to right: Sarah Reichert, Jeff Hlinka, A.J. Sprangers, John Byce, Alex Johnson
From left to right: Sarah Reichert, Jeff Hlinka, A.J. Sprangers, John Byce, Alex Johnson

Images

John is weighing out amount of PEG-DA to be used for the swelling testing
John is weighing out amount of PEG-DA to be used for the swelling testing
Sarah is pipetting out amounts of photo-inducer so that the gels will cross-link when exposed to UV radiation
Sarah is pipetting out amounts of photo-inducer so that the gels will cross-link when exposed to UV radiation
Jeff is pipetting amounts gel onto slides to be exposed to UV radiation
Jeff is pipetting amounts gel onto slides to be exposed to UV radiation
John and Sarah are happy we made our first biogel!
John and Sarah are happy we made our first biogel!
Comparison of 100 microliter aliquot to Sarah's hand
Comparison of 100 microliter aliquot to Sarah's hand
Comparison to of 100 microliter aliquot to pen
Comparison to of 100 microliter aliquot to pen

Files

Contact Information

Team Members

  • John Byce - Co-Team Leader
  • Sarah Reichert - Co-Team Leader
  • Anthony Sprangers - Communicator
  • Alexander Johnson - BSAC
  • Jeffrey Hlinka - BWIG

Advisor and Client

  • Prof. Chris Brace - Advisor
  • Neal Barney - Client
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