Point of care biosensor microfluidic cartridge
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A microfluidic cartridge that filters a sample of whole blood and delivers it to a biosensor as a Point of Care service.
Point-of-Care (POC) diagnostic biosensors play a critical role in public health. Many optical biochemical sensors are based on assays that require blood serum or plasma samples. However, extracting serum or plasma from whole blood requires specific equipment that is not compatible with the point-of-care settings. Therefore, there is a critical need for rapid, reliable and low-cost microfluidic lateral flow cartridges to disseminate new biosensors for POC applications. The expectation from this project is to design a microfluidic device that can be assembled into nanoplasmonic biosensors (chip area=1 cm2, thickness=0.5 um) that are developed in the Yesilkoy Lab. The final device should take a small quantity (100 μL) of whole blood from a finger prick, filter blood cells from whole blood within minutes (less than 5 mins), and transfer the filtered blood sample (> 25 μL) into a measurement chamber where the quantitative bioassay will take place. The total cost of the cartridge should not exceed 5$ in the final manufacturing and 50$ in the research & development phase.
- Harshal Kanade - Team Leader
- Riley Smith - Communicator
- Ryan Granowski - BSAC
- Adriana Nickels - Co-BWIG
- Lucia Hockerman - Co-BWIG
- Isabelle Counts - BPAG
Advisor and Client
- Prof. Pamela Kreeger - Advisor
- Prof. Filiz Yesilkoy - Client
- Spring 2024: Point of care biosensor microfluidic cartridge
- Fall 2023: Point of care biosensor microfluidic cartridge