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JangoBio: Designing single and multi spinner flasks for organoid culture

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The team is designing a flask that will allow for organoids to develop using acoustofluidics.

Project Overview

Culturing organoids requires the use of well-designed, spinning culture vessels to facilitate their formation from isolated stem cells. Current designs for spinner flasks and spinning bioreactors are expensive and not well suited for smaller-scale research purposes. Therefore, there is a need for a small volume, multi-well, spinning bioreactor that is reusable, inexpensive, and has the ability to modulate the rotation of each well individually for niche research purposes. In addition, most designs on the market mechanically rotate the culture fluid with an impeller or magnetic stirring approach, which can have adverse effects on the cells and organoids. However, there are current research efforts into using acoustic waves and an “acoustofluidic” technique to spin the culture fluid instead. Thus, there is also a market opportunity for a novel spinning bioreactor that uses acoustic waves to rotate the culture media. JangoBio, a regenerative stem cell company, is interested in developing a multi-well spinner flask for small-scale, research purposes that uses acoustofluidics.

Team Picture

From left to right: Sydney Heimer, Max Christopherson, Chris Wiegand, Lexi Harrod, Jonathan Izban
From left to right: Sydney Heimer, Max Christopherson, Chris Wiegand, Lexi Harrod, Jonathan Izban

Contact Information

Team Members

  • Max Christopherson - Team Leader
  • Sydney Heimer - Communicator
  • Christopher Wiegand - BSAC
  • Alexi Harrod - BWIG
  • Jonathan Izban - BPAG

Advisor and Client

  • Prof. Megan McClean - Advisor
  • Dr. Craig Atwood - Client
  • Sivan Vadakkadath Meethal - Alternate Contact

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